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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATM
All Species:
12.73
Human Site:
S49
Identified Species:
31.11
UniProt:
Q13315
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13315
NP_000042.3
3056
350687
S49
H
L
D
R
H
S
D
S
K
Q
G
K
Y
L
N
Chimpanzee
Pan troglodytes
XP_001139487
3056
350692
S49
H
L
D
R
H
S
D
S
K
Q
G
K
Y
L
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62388
3066
349469
S49
H
L
D
R
H
S
D
S
K
Q
G
K
Y
L
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001155872
3050
347768
S49
Q
L
D
R
N
S
D
S
R
R
G
N
Q
L
N
Frog
Xenopus laevis
Q9DE14
2654
301441
Zebra Danio
Brachydanio rerio
XP_002667249
1913
215524
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q5EAK6
2767
317973
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107666
3120
349933
L48
L
Q
L
D
K
H
T
L
E
G
K
S
N
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M3G7
3856
435096
W113
F
L
V
G
N
L
V
W
V
M
T
K
Y
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RZT9
2939
328678
H48
T
G
S
Q
A
E
S
H
S
Q
K
L
F
D
D
Conservation
Percent
Protein Identity:
100
99.4
N.A.
N.A.
N.A.
83.8
N.A.
N.A.
N.A.
69.5
20.5
35.1
N.A.
22.1
N.A.
N.A.
36.2
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
91.3
N.A.
N.A.
N.A.
82.8
39.9
46.3
N.A.
42.8
N.A.
N.A.
56.7
P-Site Identity:
100
100
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
60
0
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
80
0
0
N.A.
0
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
N.A.
20.8
Protein Similarity:
N.A.
N.A.
N.A.
42.5
N.A.
40.9
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
40
10
0
0
40
0
0
0
0
0
0
10
10
% D
% Glu:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% F
% Gly:
0
10
0
10
0
0
0
0
0
10
40
0
0
0
0
% G
% His:
30
0
0
0
30
10
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
30
0
20
40
0
10
10
% K
% Leu:
10
50
10
0
0
10
0
10
0
0
0
10
0
40
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
20
0
0
0
0
0
0
10
10
0
40
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
10
0
0
0
0
0
40
0
0
10
0
0
% Q
% Arg:
0
0
0
40
0
0
0
0
10
10
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
40
10
40
10
0
0
10
0
0
0
% S
% Thr:
10
0
0
0
0
0
10
0
0
0
10
0
0
0
10
% T
% Val:
0
0
10
0
0
0
10
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _